Talk:Genetic drift

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Good articleGenetic drift has been listed as one of the Natural sciences good articles under the good article criteria. If you can improve it further, please do so. If it no longer meets these criteria, you can reassess it.
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November 28, 2009Good article nomineeListed
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To Do

  • Generalize example to differing initial frequencies
  • Generalize example to combined selection/drift
  • Formula for probability of drift
  • Formula for expected (magnitude) of drift
  • Role in extinction, fixation, substitution
  • Probability of substitution
  • Balance between mutation influx and extinction/substitution
  • Neutral evolution
  • Drift -> divergence -> finds new points where selection exists
  • Gene duplication -> more drift -> new function
  • Loss of unused traits (example: sight in dark cave)
  • Diffusion models of genetic drift

Marble analogy

“To represent this reproduction, randomly select BUT DO NOT REMOVE a marble from the original jar and deposit a new marble with the same colour into a new jar.”

I struggled a little with the logic of this analogy until I understood it as amended above. If I select a kitten from a litter I take it with me.

Someone with more authority could make the change if deemed helpful. =avallone (talk) 15:02, 5 May 2024 (UTC)

Example with marbles in a jar

The example as given here makes no sense and it does not reflect what is given in reference [99, as can be easily verified. 2601:589:4801:CDB0:CD15:DF1C:C8FB:85AB (talk) 01:23, 9 December 2024 (UTC)

Drift load

I added a sentence about "drift load" which was reverted because an editor thought the term was obscure and irrelevant ("not in any of [their] genetics textbooks"). I can appreciate that, but it is in one of my genetics textbooks: Conservation and the Genomics of Populations, 3rd ed., 2022, Allendorf et. al. (Google books link below) It is a term used to describe a specific consequence of genetic drift, lowered fitness due to fixation of deleterious alleles. I think if you take a look at that textbook, or my references, you'll see drift load is not obscure to those most concerned with genetic drift, conservationists, and is highly relevant to genetic drift as a topic, being a quantifiable consequence of it. I hope you'll take another look, @Genome42, and I'd love to hear other views from any editors watching this page. Thanks!

https://books.google.com/books?id=F6JaEAAAQBAJ&newbks=1&newbks_redir=0&lpg=PP1&dq=Conservation%20and%20the%20Genomics%20of%20Populations&pg=PP1#v=onepage&q=%22drift%20load%22&f=false CarolineIngles (talk) 04:22, 19 March 2025 (UTC)

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