2,3,4,5-Tetramethoxyamphetamine
Chemical compound
From Wikipedia, the free encyclopedia
Tetramethoxyamphetamine (TeMA), or 2,3,4,5-tetramethoxyamphetamine (2,3,4,5-TeMA), also known as 2-methoxy-TMA or 3-methoxy-TMA-2, is a drug of the phenethylamine and amphetamine families related to mescaline (3,4,5-trimethoxyphenethylamine).[1][2]
- None
- CA: Schedule I
- UK: Class A
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| Other names | TeMA; TA; 2,3,4,5-TeMA; 2,3,4,5-Tetramethoxyamphetamine; 2,3,4,5-Tetramethoxyphenylisopropylamine; 2-Methoxy-TMA; 2-Methoxy-3,4,5-TMA; 3-Methoxy-TMA-2; 3-Methoxy-2,4,5-TMA |
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| Formula | C13H21NO4 |
| Molar mass | 255.314 g·mol−1 |
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In his book PiHKAL (Phenethylamines I Have Known And Loved), Alexander Shulgin lists TeMA's "probably above 50 mg" orally and its duration as unknown.[1][2] In an earlier publication, it was said to produce threshold effects at a dose of 30 mg orally and long-lived effects at a dose of 50 mg orally.[2] The effects of TeMA have been reported to include disinhibition, intoxication, pupil dilation, and headache.[1][2] It is said to be roughly 6 times as potent as mescaline.[3] TeMA has been said to be the only amphetamine with more than three methoxy groups known to be hallucinogenic.[2] However, the psychedelic properties of TeMA were subsequently questioned.[4]
The chemical synthesis of TeMA has been described.[1]
TeMA was first described in the scientific literature by at least 1975.[3][2] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.[1] The drug is a controlled substance in Canada under phenethylamine blanket-ban language.[5]