UBE1L2

Ubiquitin-like modifier-activating enzyme 6 is a protein that in humans is encoded by the UBA6 gene.^[5][6]

AliasesUBA6, E1-L2, MOP-4, UBE1L2, ubiquitin like modifier activating enzyme 6

External IDsOMIM: 611361; MGI: 1913894; HomoloGene: 10080; GeneCards: UBA6; OMA:UBA6 - orthologs

Chr.Chromosome 4 (human)^[1]

End67,701,155 bp^[1]

Quick facts UBA6, Identifiers ...

UBA6
Identifiers
Aliases	UBA6, E1-L2, MOP-4, UBE1L2, ubiquitin like modifier activating enzyme 6
External IDs	OMIM: 611361; MGI: 1913894; HomoloGene: 10080; GeneCards: UBA6; OMA:UBA6 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q13.2 Start 67,612,652 bp[1] End 67,701,155 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 E1 Start 86,257,146 bp[2] End 86,320,662 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte epithelium of nasopharynx Achilles tendon gingival epithelium germinal epithelium mucosa of paranasal sinus endothelial cell ventricular zone corpus callosum oral cavity Top expressed in otic vesicle hand spermatogonium trigeminal ganglion primitive streak superior cervical ganglion otolith organ maxillary prominence utricle pineal gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function FAT10 activating enzyme activity nucleotide binding ligase activity protein binding ATP binding ubiquitin-like modifier activating enzyme activity ubiquitin activating enzyme activity Cellular component cytosol cytoplasm Biological process dendritic spine development amygdala development learning hippocampus development ubiquitin-dependent protein catabolic process locomotory behavior protein ubiquitination cellular response to DNA damage stimulus protein modification by small protein conjugation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55236 231380 Ensembl ENSG00000033178 ENSMUSG00000035898 UniProt A0AVT1 H0Y9U5 Q8C7R4 RefSeq (mRNA) NM_018227 NM_172712 RefSeq (protein) NP_060697 NP_766300 Location (UCSC) Chr 4: 67.61 – 67.7 Mb Chr 5: 86.26 – 86.32 Mb PubMed search [3] [4]
Wikidata
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