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Outline for Article: Inverted Repeat --- (talk page for Inverted Repeat article)

1. Lead paragraph (brief introduction)
2. Definition & Examples
   1. cartoon to explain - Jim Perry has an idea for this - to be developed in future weeks
   2. Examples of Inverted Repeats
   3. Other types of repeats
      1. direct repeats vs. inverted repeats
      2. palindromes vs. inverted repeats
3. Biological Features & Functionality
   1. Origin of Inverted Repeats - How they are introduced.
   2. Conditions that favor synthesis of Inverted Repeats.
   3. Most common biological functions using Inverted Repeats.
   4. Regions where presence is obligatory.
   5. Location of inverted repeats in the genome - how, why and where
   6. Inverted repeats common in different organisms
4. Databases of Inverted Repeats (with External Links as appropriate)
5. References

Information about the References

• Inverted Repeats and DNA replication. 1996 review article. Might be good (or might be too old?) ^[1]
• RNA related. Is CRISPR a potential category? CRISPR = Clustered Regularly Interspaced Short Palindromic Repeats ^[2]
• palindrome-mediated translocations are localized at the center of palindromic AT-rich repeats (PATRRs)^[3]
• DNA inverted repeats in the genome. Might be a special category? ^[4]
• Folded DNA - Hairpins ^[5]
• Inverted repeats in the male-specific region of the human chromosome Y(MSY) ^[6]
• Instability of palindromes by formation of a hairpin or cruciform structure and the resultant chromosomal deletion or translocation.^[7]
• Holliday-junction resolution in homologous recombination and coding joint formation in rearrangement of antigen-receptor genes.^[8]
• Hypertensive crises caused by inverted left atrial appendage.^[9]
• Families of inverted repeat fold transporters.^[10]
• Size and distribution of inverted repeats in D. melanogaster DNA.^[11]
• Transient blindness and transurethral resection.^[12]
• Inverted sequences among families of repetition frequencies.^[13]
• Faulty application fork maintenance pathways at nonallelic repeats and cancer and genomic disorders and speciation.^[14]
• The properties of inverted repeat sequences in wheat nuclear DNA.^[15]
• Invereted repeats in spinach, corn and lettuce.^[16]
• Inverted repeats in MDg3 of Drosophila melanogaster.^[17]

References:

Possible Images

We will need to get permission before using these unless already under the proper license:

Hairpin Image: http://course1.winona.edu/sberg/ILLUST/hairpin.JPG

Open Access Article: http://www.biomedcentral.com/1471-2164/7/73/

See Figure 3 in this article for a good example of an inverted repeat

Here is the link to the photo: http://www.biomedcentral.com/1471-2164/7/73/figure/F3

Palidrome and mirror repeats: http://www.siumed.edu/~bbartholomew/images/Lehninger/img035.gif

Examples of inverted repeats: http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/RecognitionHelix.gif

Suggested Improvements: These are listed on the talk page for the article

LINK: Article talk page (for the Inverted Repeat article)