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"Elucidating the mechanism of transcription initiation by RNA polymerases (RNAP) is essential for understanding gene transcription and regulation. Although several models such as DNA scrunching, RNAP translation, and RNAP rotation have been proposed, the mechanism of initiation by T7 RNAP has remained unclear."[1]
"In addition to DNA scrunching, FRET studies also indicated moderate rotation or hinging movement of the promoter during the synthesis of 4 to 7 nt RNA." [1]


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