Vesicular glutamate transporter 3

SLC17A8
Identifiers
Aliases	SLC17A8, DFNA25, VGLUT3, solute carrier family 17 member 8
External IDs	OMIM: 607557; MGI: 3039629; HomoloGene: 13584; GeneCards: SLC17A8; OMA:SLC17A8 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	100,422,055 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	89,457,115 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; oocyte; ; secondary oocyte; ; prefrontal cortex; ; mucosa of transverse colon; ; rectum; ; hypothalamus; ; amygdala; ; caudate nucleus;
	Top expressed in
	organ of Corti; ; vestibular labyrinth; ; pons; ; liver; ; utricle; ; basal forebrain; ; striatum of neuraxis; ; neural layer of retina; ; ileum; ; ampullary crest;
	More reference expression data
	n/a
Gene ontology
Molecular function	symporter activity; L-glutamate transmembrane transporter activity; neurotransmitter transmembrane transporter activity;
Cellular component	cytoplasm; axon terminus; integral component of membrane; multivesicular body; perikaryon; membrane; synapse; excitatory synapse; basal dendrite; pericellular basket; synaptic vesicle membrane; cell junction; soma; dendrite; glial limiting end-foot; neuron projection; cytoplasmic vesicle; apical dendrite; integral component of synaptic vesicle membrane;
Biological process	cochlea development; sodium ion transport; ion transport; hearing; brain development; neurotransmitter transport; neural retina development; L-glutamate transmembrane transport; transmembrane transport; synaptic transmission, glutamatergic; regulation of synapse structure or activity; neurotransmitter loading into synaptic vesicle;
	Sources:Amigo / QuickGO
Orthologs
	246213
	216227
	ENSG00000179520
	ENSMUSG00000019935
	Q8NDX2
	Q8BFU8
	NM_139319; NM_001145288
	NM_182959; NM_001310710
	NP_001138760; NP_647480
	NP_001297639; NP_892004
	Wikidata
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