Wetland virus
Pathogenic virus
From Wikipedia, the free encyclopedia
Wetland virus or WELV is a tick borne Orthonairovirus which can infect humans. It can produce fever, headache, dizziness, malaise, arthritis and less commonly petechiae, localized lymphadenopathy. Complications may include neurological symptoms.[1][2]
| Wetland virus | |
|---|---|
Virus classification  | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Negarnaviricota |
| Class: | Bunyaviricetes |
| Order: | Hareavirales |
| Family: | Nairoviridae |
| Genus: | Orthonairovirus |
| Virus: | Wetland virus |
Virology
The Wetland virus orthonairovirus (WELV) is a member of the genus Orthonairovirus, family Nairoviridae[1] of RNA viruses. It was first identified in 2019 in a Chinese person in Jinzhou, Liaoning province Northeast China after a visit to a wetland park in Yakeshi, Inner Mongolia. Three different strains were identified one from the patient and two from ticks.[1]
Its sequence is most similar to the Tofla virus from Japan.[1]
Hosts and transmission
The Wetland virus was found in mice, sheep, pigs, cows, and horses, but not dogs. It was found in about 2% of 14,500 different ticks in Northeast China with the highest prevalence (6%) in Haemaphysalis concinna.[2]
Signs and symptoms
Symptoms of infection with the Wetland virus are fever, headache, dizziness, malaise, myalgia (muscle pain), arthritis, and back pain. Less commonly there are petechiae and localized lymphadenopathy.[1] One person also had severe neurological symptoms, but all recovered without sequelae.[1] Symptoms and signs resemble those of Crimean–Congo hemorrhagic fever, and the differential diagnosis includes severe fever with thrombocytopenia syndrome and spotted fever.[1]
Treatment
Nucleoside analogs have been shown to have significant promise in treating WELV virus infections[3] and is in clinical stages.