Weyer's ulnar ray/oligodactyly syndrome
From Wikipedia, the free encyclopedia
SymptomsUlnar ray deficit, heart, renal and splenic abnormalities and ectrodactyly
ComplicationsPossible death (due to e.g. the cardiac and renal problems)
Usual onsetBirth
| Weyer's ulnar ray/oligodactyly syndrome | |
|---|---|
| Specialty | Medical genetics |
| Symptoms | Ulnar ray deficit, heart, renal and splenic abnormalities and ectrodactyly |
| Complications | Possible death (due to e.g. the cardiac and renal problems) |
| Usual onset | Birth |
| Duration | Life-long |
| Causes | Genetic mutation |
| Prevention | None |
| Prognosis | Ok |
| Frequency | Very rare. only 4 families known to carry the gene/be affected by the gene |
| Deaths | - |
Weyer's ulnar ray/oligodactyly syndrome is a rare multi-systemic genetic disorder which is characterized by ectrodactyly, ulnar, radial, or fibular ray deficit, and heart, single central incisor, splenic, and renal abnormalities. Cleft lip/palate and hypoplasia of the mandibles have also been observed.[1] It is thought to be inherited in an autosomal recessive pattern.[2] It was first discovered in 1957 by Weyers et al. Only four families worldwide are known to be affected by the disorder.[3][4][5]
