ZNF277

ZNF277
Identifiers
Aliases	ZNF277, NRIF4, ZNF277P, zinc finger protein 277
External IDs	OMIM: 605465; MGI: 1890393; GeneCards: ZNF277
Gene location (Human)
Chr.	Chromosome 7 (human)
End	112,343,934 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	40,495,901 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; monocyte; ; germinal epithelium; ; islet of Langerhans; ; body of pancreas; ; ganglionic eminence; ; jejunal mucosa; ; oocyte; ; skin of thigh; ; gallbladder;
	Top expressed in
	primary oocyte; ; cumulus cell; ; efferent ductule; ; vas deferens; ; abdominal wall; ; medial ganglionic eminence; ; zygote; ; secondary oocyte; ; ovary; ; endocardial cushion;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; metal ion binding; nucleic acid binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	regulation of cellular senescence; regulation of transcription, DNA-templated; transcription, DNA-templated; cellular response to hydrogen peroxide; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	11179
	246196
	ENSG00000198839
	ENSMUSG00000055917
	Q9NRM2
	E9Q6D6
	NM_021994
	NM_172575; NM_178845
	NP_068834
	NP_766163; NP_849173
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 277 is a protein that in humans is encoded by the ZNF277 gene (previously ZNF277P).^[5]^[6]^[7]^[8] ZNF277 is predicted to be a transcription factor which is involved in regulating cellular senescence.^[9] The gene ZNF277 was truncated from its ancestral form, leading to it be labeled as a pseudogene in some places, but is now thought to produce a functionally modified protein.^[7]^[8]