(KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase
Class of enzymes
From Wikipedia, the free encyclopedia
(KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.13, KDO transferase, waaA (gene), kdtA (gene), Kdo transferase, 3-deoxy-D-manno-oct-2-ulosonic acid transferase, 3-deoxy-manno-octulosonic acid transferase) is an enzyme with systematic name CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase.[1][2] This enzyme catalyses the following chemical reaction
- alpha-Kdo-(2->6)-lipid IVA + CMP-alpha-Kdo alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP
| (KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.99.13 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The bifunctional enzyme from Escherichia coli transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA.
See also
- EC 2.4.99.12, lipid IVA 3-deoxy-D-manno-octulosonic acid transferase
