(S)-2-hydroxypropylphosphonic acid epoxidase

Class of enzymes From Wikipedia, the free encyclopedia

(S)-2-hydroxypropylphosphonic acid epoxidase (EC 1.11.1.23, HPP epoxidase, HppE, 2-hydroxypropylphosphonic acid epoxidase, Fom4, (S)-2-hydroxypropylphosphonate epoxidase) is an enzyme with systematic name (S)-2-hydroxypropylphosphonate,NADH:oxygen epoxidase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

2D representation of the chemical structure of Q27104552.
(S)-2-hydroxypropylphosphonic acid
 
H2O2
2 H2O
Reversible left-right reaction arrow with minor forward substrate(s) from top left, minor forward product(s) to top right, minor reverse substrate(s) from bottom right and minor reverse product(s) to bottom left
H2O2
2 H2O
 

(S)-2-hydroxypropylphosphonic acid epoxidase contains one non-heme iron centre per monomer. The product is the antibiotic fosfomycin.[6][7]

References

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