(S)-corytuberine synthase
Class of enzymes
From Wikipedia, the free encyclopedia
(S)-corytuberine synthase is an enzyme purified from the plant Coptis japonica (Japanese goldthread),[1] with EC number EC 1.14.19.51 and CYP Symbol CYP80G2. It catalyses an intramolecular C-C phenol coupling of (S)-reticuline to (S)-corytuberine in a pathway leading to magnoflorine.[2][3]
| (S)-corytuberine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.19.51 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
(S)-corytuberine synthase is a cytochrome P450 protein containing heme. It requires a partner cytochrome P450 reductase for functional expression. This uses nicotinamide adenine dinucleotide phosphate (NADPH).[4]