(S)-corytuberine synthase

Class of enzymes From Wikipedia, the free encyclopedia

(S)-corytuberine synthase is an enzyme purified from the plant Coptis japonica (Japanese goldthread),[1] with EC number EC 1.14.19.51 and CYP Symbol CYP80G2. It catalyses an intramolecular C-C phenol coupling of (S)-reticuline to (S)-corytuberine in a pathway leading to magnoflorine.[2][3]

 
 
O2
2 H2O
Rightward reaction arrow with minor substrate(s) from top left and minor product(s) to top right
 
 
 
2D representation of the chemical structure of Q27155145.
(S)-corytuberine
 

(S)-corytuberine synthase is a cytochrome P450 protein containing heme. It requires a partner cytochrome P450 reductase for functional expression. This uses nicotinamide adenine dinucleotide phosphate (NADPH).[4]

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