(S)-limonene 7-monooxygenase
Class of enzymes
From Wikipedia, the free encyclopedia
(S)-limonene 7-monooxygenase (EC 1.14.14.52) is an enzyme that catalyzes the chemical reaction
-Perillyl_alcohol.svg)
-Limonen.svg)
| (S)-limonene 7-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.14.52 | ||||||||
| CAS no. | 122653-75-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The four substrates of this enzyme are (â)-(S)-limonene, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen, and a proton. Its products are (â)-perillyl alcohol, oxidised NADP+, and water.[1][2]
This enzyme is a cytochrome P450 protein containing heme. This oxidoreductase, which uses molecular oxygen as oxidant is in a group with systematic name (S)-limonene,NADPH:oxygen oxidoreductase (7-hydroxylating). Other names in common use include (â)-limonene 7-monooxygenase, (â)-limonene hydroxylase, (â)-limonene monooxygenase, and (â)-limonene,NADPH:oxygen oxidoreductase (7-hydroxylating).[1] In Perilla frutescens it is part of the biosynthetic pathway to perillaldehyde.[2]
