1,8-Naphthyridine
Chemical compound
From Wikipedia, the free encyclopedia
1,8-Naphthyridine is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric naphthyridines, a subset of diazanaphthalenes with nitrogen in the separate rings.[2][3] Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.[4]
| Names | |
|---|---|
| Preferred IUPAC name
1,8-Naphthyridine[1] | |
| Identifiers | |
3D model (JSmol) |
|
| 109347 | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.201.052 |
| EC Number |
|
| 27124 | |
PubChem CID |
|
| UNII | |
CompTox Dashboard (EPA) |
|
| |
| |
| Properties | |
| C8H6N2 | |
| Molar mass | 130.150 g·molâ1 |
| Appearance | yellow solid |
| Density | 1.359 g/cm3 |
| Melting point | 98â99 °C (208â210 °F; 371â372 K) |
| Hazards | |
| GHS labelling: | |
| Warning | |
| H315, H319, H335 | |
| P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
Coordination chemistry
With flanking nitrogen centers, 1,8-naphthyridine serves as a binucleating ligand in coordination chemistry.[5][6]
