1-Deoxy-D-xylulose 5-phosphate
Chemical compound
From Wikipedia, the free encyclopedia
1-Deoxy-d-xylulose 5-phosphate is a biosynthetic intermediate in the non-mevalonate pathway.[1]
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| Names | |
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| IUPAC name
1-Deoxy-D-xylulose 5-(dihydrogen phosphate) | |
| Systematic IUPAC name
(2R,3S)-2,3-Dihydroxy-4-oxopentyl dihydrogen phosphate | |
| Other names
DOXP | |
| Identifiers | |
3D model (JSmol) |
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| KEGG | |
| MeSH | 1-deoxy-D-xylulose+5-phosphate |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C5H11O7P | |
| Molar mass | 214.11 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Function
The enzyme involved in making 1-deoxy-d-xylulose 5-phosphate (DXP) is DXP synthase.[2] The mechanism follows a catalysis of decarboxylative condensation of pyruvate and d-glyceraldehyde 3-phosphate to produce DXP.[2][3] In addition, the molecule is involved in making thiamine (vitamin B1) and pyridoxol (vitamin B6).[2]
The non-mevalonate pathway intermediate 1-deoxy-d-xylulose 5-phosphate (DXP) also acts as a precursor in making isoprenoids in many species such as bacteria, plants, and apicomplexan parasites, contributing to biological diversity.[1]