1-Fluoronaphthalene
Chemical compound
From Wikipedia, the free encyclopedia
1-Fluornaphthalene is an organofluorine chemical compound from the group of naphthalene derivatives and fluoroaromatics. Its chemical formula is C
10H
7F.[1]
| |
| Names | |
|---|---|
| Preferred IUPAC name
1-Fluoronaphthalene | |
| Other names
α-fluoronaphthalene | |
| Identifiers | |
3D model (JSmol) |
|
| ChemSpider | |
| ECHA InfoCard | 100.005.717 |
| EC Number |
|
PubChem CID |
|
| UNII | |
CompTox Dashboard (EPA) |
|
| |
| |
| Properties | |
| C 10H 7F | |
| Appearance | Colorless liquid |
| Melting point | −13 °C (9 °F; 260 K) |
| Boiling point | 215 °C (419 °F; 488 K) |
| insoluble | |
| Hazards | |
| GHS labelling: | |
 | |
| Warning | |
| Flash point | 65 °C (149 °F; 338 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
Synthesis
1-Fluoronaphthalene can be obtained by reacting naphthalene with Selectfluor.[2]
Properties
1-Fluoronaphthalene is a colorless, combustible liquid, which is insoluble in water.[3]
Applications
1-Fluoronaphthalene was used for the tert-butyllithium-mediated synthesis of 6-substituted phenanthridines. It has also been used in the synthesis of LY248686, a potent inhibitor of serotonin and norepinephrine uptake.
1-Fluoronaphthalene is also used as a component of the Organic Check Material mounted in canisters on Mars Science Laboratory Curiosity rover. It's used for calibrating the Sample Analysis at Mars (SAM) instrument suite, being a synthetic organic compound not found in nature on Earth and not expected on Mars.[4]