11C-UCB-J

11C-UCB-J
Names
	Preferred IUPAC name (4R)-1-{[3-(11C)Methylpyridin-4-yl]methyl}-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one
	Other names [11C]UCB-J; 11C-UCB-J; [11C]UCB-J
Identifiers
CAS Number	2098041-11-1 ;
3D model (JSmol)	Interactive image;
ChemSpider	103882818;
PubChem CID	74539761;
UNII	99PJR3QL3Y ;
CompTox Dashboard (EPA)	DTXSID801127334 ;
	InChI InChI=1S/C17H15F3N2O/c1-10-7-21-3-2-11(10)8-22-9-13(6-16(22)23)12-4-14(18)17(20)15(19)5-12/h2-5,7,13H,6,8-9H2,1H3/t13-/m0/s1/i1-1 Key: RFSDYRVOGWHOFT-XOTOJZTHSA-N;
	SMILES [11CH3]C1=CN=CC=C1CN1C[C@H](CC1=O)C1=CC(F)=C(F)C(F)=C1;
Properties
Chemical formula	C17H15F3N2O
Molar mass	320.315 gÂ·molâ1
	Except where otherwise noted, data are given for materials in their standard state (at 25 Â°C [77 Â°F], 100 kPa). Infobox references

11C-UCB-J is a PET tracer for imaging the synaptic vesicle glycoprotein 2A in the human brain.^[1]

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It is used to study the brain changes associated with several diseases including Alzheimer's disease,^[2]^[3] schizophrenia,^[4]^[5] and depression.^[6]

References

Names

Preferred IUPAC name (4R)-1-{[3-(¹¹C)Methylpyridin-4-yl]methyl}-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one
Other names [11C]UCB-J; ¹¹C-UCB-J; [¹¹C]UCB-J
Identifiers
CAS Number	2098041-11-1^Y
3D model (JSmol)	Interactive image
ChemSpider	103882818
PubChem CID	74539761
UNII	99PJR3QL3Y^Y
CompTox Dashboard (EPA)	DTXSID801127334
InChI InChI=1S/C17H15F3N2O/c1-10-7-21-3-2-11(10)8-22-9-13(6-16(22)23)12-4-14(18)17(20)15(19)5-12/h2-5,7,13H,6,8-9H2,1H3/t13-/m0/s1/i1-1 Key: RFSDYRVOGWHOFT-XOTOJZTHSA-N
SMILES [11CH3]C1=CN=CC=C1CN1C[C@H](CC1=O)C1=CC(F)=C(F)C(F)=C1
Properties
Chemical formula	C₁₇H₁₅F₃N₂O
Molar mass	320.315 gÂ·mol^â1
Except where otherwise noted, data are given for materials in their standard state (at 25 Â°C [77 Â°F], 100 kPa). Infobox references