13-Fluorolysergol

13-Fluorolysergol, specifically as the (+)-enantiomer (+)-13-fluorolysergol, is a selective serotonin 5-HT_2A receptor weak partial agonist or antagonist of the ergoline family.^[1][2] It is highly selective for activation of the serotonin 5-HT_2A receptor over the serotonin 5-HT_2B and 5-HT_2C receptors (EC₅₀Tooltip half-maximal effective concentration = >10,000 nM).^[1][2] (+)-13-Fluorolysergol has relatively weak maximal efficacy in activating the serotonin 5-HT_2A receptor (E_maxTooltip maximal efficacy = 17%).^[1][2] It is a derivative of lysergol.^[1][2]

Other names(13-Fluoro-6-methyl-9,10-didehydroergolin-8β-yl)methanol

Drug classSelective serotonin 5-HT_2A receptor weak partial agonist or antagonist

PubChem CID

• 132505474

FormulaC₁₆H₁₇FN₂O

Quick facts Clinical data, Other names ...

13-Fluorolysergol

Clinical data
Other names	(13-Fluoro-6-methyl-9,10-didehydroergolin-8β-yl)methanol
Drug class	Selective serotonin 5-HT2A receptor weak partial agonist or antagonist
Identifiers
IUPAC name [(6aR,9R)-2-fluoro-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]methanol
PubChem CID	132505474
Chemical and physical data
Formula	C16H17FN2O
Molar mass	272.323 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1C[C@@H](C=C2[C@H]1CC3=CNC4=CC(=CC2=C34)F)CO
InChI InChI=1S/C16H17FN2O/c1-19-7-9(8-20)2-12-13-4-11(17)5-14-16(13)10(6-18-14)3-15(12)19/h2,4-6,9,15,18,20H,3,7-8H2,1H3/t9-,15-/m1/s1 Key:UBKCOUCTZVGLJQ-RFAUZJTJSA-N

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