16S rRNA (guanine1207-N2)-methyltransferase

Class of enzymes From Wikipedia, the free encyclopedia

16S rRNA (guanine1207-N2)-methyltransferase (EC 2.1.1.172, m2G1207 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine1207-N2)-methyltransferase.[1][2] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine1207 in 16S rRNA S-adenosyl-L-homocysteine + N2-methylguanine1207 in 16S rRNA

The enzyme reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA.

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