17-Phenylandrostenol

17-Phenylandrostenol (17-PA), or (3α,5α)-17-phenylandrost-16-en-3-ol, is a steroid drug which binds to GABA_A receptors. It acts as an antagonist against the sedative effects of neuroactive steroids, but has little effect when administered by itself, and does not block the effects of benzodiazepines or barbiturates.^[1][2]

Other names(3α,5α)-17-Phenyl-androst-16-en-3-ol

CAS Number

• 694438-95-4 ^N

PubChem CID

• 25068278

ChemSpider

• 21475142 ^Y

Quick facts Clinical data, Other names ...

17-Phenylandrostenol

Clinical data
Other names	(3α,5α)-17-Phenyl-androst-16-en-3-ol
Identifiers
IUPAC name (3R,5S,8R,9S,10S,13S,14S)-10,13-dimethyl-17-phenyl- 2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
CAS Number	694438-95-4 N
PubChem CID	25068278
ChemSpider	21475142 Y
Chemical and physical data
Formula	C25H34O
Molar mass	350.546 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[C@]12CC[C@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C5=CC=CC=C5)C)O
InChI InChI=1S/C25H34O/c1-24-14-12-19(26)16-18(24)8-9-20-22-11-10-21(17-6-4-3-5-7-17)25(22,2)15-13-23(20)24/h3-7,10,18-20,22-23,26H,8-9,11-16H2,1-2H3/t18-,19+,20-,22-,23-,24-,25+/m0/s1 Y Key:SINAMTXBCYKFDL-WBJZGETLSA-N Y
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