17α-Bromoprogesterone

17α-Bromoprogesterone (17α-BP) is a progestin which was first described in 1957 and was never marketed.^[1][2][3][4] It is about twice as potent as progesterone in terms of progestogenic activity in animal bioassays.^[1] 17α-BP is a parent compound of haloprogesterone (6α-fluoro-17α-bromoprogesterone) and 6α-methyl-17α-bromoprogesterone.^[5]

Other names17α-BP; 17α-Bromopregn-4-ene-3,20-dione

Drug classProgestogen; Progestin

CAS Number

• 28449-24-3

PubChem CID

• 68524848

Quick facts Clinical data, Other names ...

17α-Bromoprogesterone

Clinical data
Other names	17α-BP; 17α-Bromopregn-4-ene-3,20-dione
Drug class	Progestogen; Progestin
Identifiers
IUPAC name (8R,9S,10R,13S,14S,17R)-17-Acetyl-17-bromo-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
CAS Number	28449-24-3
PubChem CID	68524848
ChemSpider	103882972
UNII	YBT8Y54Z9P
Chemical and physical data
Formula	C21H29BrO2
Molar mass	393.365 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)Br
InChI InChI=1S/C21H29BrO2/c1-13(23)21(22)11-8-18-16-5-4-14-12-15(24)6-9-19(14,2)17(16)7-10-20(18,21)3/h12,16-18H,4-11H2,1-3H3/t16-,17+,18+,19+,20+,21+/m1/s1 Key:IENASMFTJRLBJP-CEGNMAFCSA-N

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