Heavily favored Duke opened the scoring early in the second quarter, and intercepted Nebraska quarterback Don Erway on NU's ensuing drive to set up another touchdown, taking a 14–0 lead into halftime.[2] Early in the second half, the Cornhuskers took advantage of a botched Blue Devils punt to cut the deficit in half, but it would be NU's only points of the game. Duke took control behind All-American running back Bob Pascal, who both teams with ninety-one rushing yards.[2] Three late Blue Devils touchdowns sealed a dominant victory.[4]
| Qtr | Team | Detail[5] | Duke | NU |
| 2 | Duke | Bob Pascal 2-yd run (Jim Nelson kick) | 7 | 0 |
| Duke | Jerry Kocourek 5-yd pass from Jerry Barger (Nelson kick) | 14 | 0 |
| 3 | NU | Don Comstock 3-yd run (Bob Smith kick) | 14 | 7 |
| Duke | Sonny Sorrell 5-yd pass from Barger (kick failed) | 20 | 7 |
| 4 | Duke | Nick McKeithan 1-yd run (Nelson kick) | 27 | 7 |
| Duke | Sam Eberdt 3-yd run (Nelson kick) | 34 | 7 |
| Statistic[5] | Duke | Nebraska |
| First downs | 23 | 6 |
| Rushes–yards | 64–288 | 34–84 |
| Comp.–att.–yards | 7–13–82 | 1–9–26 |
| Total offense | 370 | 110 |
| Turnovers | 1 | 2 |
| Punts–average | 5–23.6 | 7–28.9 |
| Penalties–yards | 2–30 | 2–20 |