The 1961 Westminster Titans football team represented Westminster College of New Wilmington, Pennsylvania. In their tenth year under head coach Harold Burry, the team compiled a 6–2 record (4–1 against WPC opponents) and won the WPC championship.
The 1961 Grove City Wolverines football team represented Grove City College of Grove City, Pennsylvania. In their sixth year under head coach Jack Behringer, the team compiled a 5–4 record (2–0 against WPC opponents) and finished in second place in the WPC.
The 1961 Waynesburg Yellow Jackets football team represented Waynesburg University of Waynesburg, Pennsylvania. In their third year under head coach Peter Mazzaferro, the team compiled a 6–2 record (2–2 against WPC opponents) and finished in a tie for third place in the WPC.
The 1961 Saint Vincent Bearcats football team represented Saint Vincent College of Latrobe, Pennsylvania. In their 14th year under head coach Al DeLuca, the team compiled a 3–3–1 record (2–2 against WPC opponents) and finished in a tie for third place in the WPC.
The 1961 Geneva Golden Tornadoes football team represented Geneva College of Beaver Falls, Pennsylvania. In their ninth year under head coach Byron E. Morgan, the team compiled a 4–4 record (2–2 against WPC opponents) and finished in a tie for third place in the WPC.
The 1961 Carnegie Tech Tartans football team represented Carnegie Institute of Technology (now known as Carnegie Mellon University) of Pittsburgh, Pennsylvania. In their second year under head coach Edward Hirshberg, the team compiled a 1–7 record (0–4 against WPC opponents) and finished in last place in the WPC.
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