2,3-Dimethoxyphenethylamine

2,3-Dimethoxyphenethylamine (2,3-DMPEA), also known as DMPEA-2, is a drug of the phenethylamine family related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine).^[1][2] It is one of the positional isomers of dimethoxyphenethylamine.^[1]

Other names2,3-DMPEA; DMPEA-2

ATC code

• None

CAS Number

• 3213-29-4

PubChem CID

• 137858

Quick facts Clinical data, Other names ...

2,3-Dimethoxyphenethylamine

Clinical data
Other names	2,3-DMPEA; DMPEA-2
ATC code	None
Identifiers
IUPAC name 2-(2,3-dimethoxyphenyl)ethanamine
CAS Number	3213-29-4
PubChem CID	137858
ChemSpider	121507
UNII	LUW5Z6DJ9Q
CompTox Dashboard (EPA)	DTXSID10185913
ECHA InfoCard	100.154.035
Chemical and physical data
Formula	C10H15NO2
Molar mass	181.235 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC=CC(=C1OC)CCN
InChI InChI=1S/C10H15NO2/c1-12-9-5-3-4-8(6-7-11)10(9)13-2/h3-5H,6-7,11H2,1-2H3 Key:XKBUFTXNLBWTFP-UHFFFAOYSA-N

Close

In contrast to various other phenethylamines like β-phenethylamine and amphetamine, it showed little activity in terms of induction of norepinephrine release in vitro.^[3] The effects of 2,3-DMPEA in humans have not been reported and are unknown.^[1]

2,3-DMPEA was first described in the scientific literature by at least 1965.^[1][2] It was included as an entry in Alexander Shulgin's 2011 book The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds.^[1]