2-haloacid dehalogenase (configuration-inverting)
Class of enzymes
From Wikipedia, the free encyclopedia
2-haloacid dehalogenase (configuration-inverting) (EC 3.8.1.10, 2-haloalkanoic acid dehalogenase, 2-haloalkanoid acid halidohydrolase, DL-2-haloacid dehalogenase, DL-2-haloacid dehalogenase (inversion of configuration), DL-2-haloacid halidohydrolase (inversion of configuration), DL-DEXi, (R,S)-2-haloacid dehalogenase (configuration-inverting)) is an enzyme with systematic name (S)-2-haloacid dehalogenase (configuration-inverting).[1][2][3][4][5][6][7][8][9] This enzyme catalyses the following chemical reaction
- (1) (S)-2-haloacid + H2O (R)-2-hydroxyacid + halide
- (2) (R)-2-haloacid + H2O (S)-2-hydroxyacid + halide
| 2-haloacid dehalogenase (configuration-inverting) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.8.1.10 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme dehalogenates both (S)- and (R)-2-haloalkanoic acids.