2-hydroxyhexa-2,4-dienoate hydratase

2-hydroxyhexa-2,4-dienoate hydratase (EC 4.2.1.132, tesE (gene), hsaE (gene)) is an enzyme with systematic name 4-hydroxy-2-oxohexanoate hydro-lyase ((2Z,4Z)-2-hydroxyhexa-2,4-dienoate-forming).^[1] This enzyme catalyses the following chemical reaction

4-hydroxy-2-oxohexanoate ${\displaystyle \rightleftharpoons }$ (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H₂O

This enzyme catalyses a late step in the bacterial steroid degradation pathway.