2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
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| OHCU decarboxylase | |||||||||
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| Identifiers | |||||||||
| Symbol | OHCU_decarbox | ||||||||
| Pfam | PF09349 | ||||||||
| InterPro | IPR018020 | ||||||||
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In molecular biology 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (OHCU decarboxylase) EC 4.1.1.n1 is an enzyme involved in purine catabolism. It catalyses the decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) into S(+)-allantoin.[1][2] It is the third step of the conversion of uric acid (a purine derivative) to allantoin. Step one is catalysed by urate oxidase and step two is catalysed by hydroxyisourate hydrolase.[3][4]