South Carolina announced its 2016 football schedule on October 29, 2015. The 2016 schedule consisted of seven home and five away games in the regular season. The Gamecocks hosted SEC foes Georgia, Missouri, Tennessee, and Texas A&M, and traveled to Florida, Kentucky, Mississippi State, and Vanderbilt.[8]
For the tenth year, the Gamecocks opened their season on a Thursday. The team hosted three out of four of its non–conference games which were against Clemson (from the ACC), East Carolina (from the American), Massachusetts (from the MAC), and Western Carolina (from the Southern Conference).
More information Date, Time ...
| Date | Time | Opponent | Site | TV | Result | Attendance |
|---|
| September 1 | 8:00 p.m. | at Vanderbilt | | ESPN | W 13–10 | 30,304 |
| September 10 | 7:00 p.m. | at Mississippi State | | ESPN2 | L 14–27 | 57,763 |
| September 17 | 4:00 p.m. | East Carolina* | | SECN | W 20–15 | 80,384 |
| September 24 | 7:30 p.m. | at Kentucky | | SECN | L 10–17 | 51,702 |
| October 1 | 4:00 p.m. | No. 9 Texas A&M | - Williams-Brice Stadium
- Columbia, SC
| SECN | L 13–24 | 78,245 |
| [a] | 2:30 p.m. | Georgia | - Williams-Brice Stadium
- Columbia, SC (rivalry)
| SECN | L 14–28 | 77,221 |
| October 22 | 12:00 p.m. | Massachusetts* | - Williams-Brice Stadium
- Columbia, SC
| SECN | W 34–28 | 73,428 |
| October 29 | 7:15 p.m. | No. 18 Tennessee | - Williams-Brice Stadium
- Columbia, SC (rivalry)
| ESPN2 | W 24–21 | 78,696 |
| November 5 | 4:00 p.m. | Missouri | - Williams-Brice Stadium
- Columbia, SC (Mayor's Cup)
| SECN | W 31–21 | 73,817 |
| November 12 | 12:00 p.m. | at No. 22 Florida | | CBS | L 7–20 | 89,614 |
| November 19 | 4:00 p.m. | Western Carolina* | - Williams-Brice Stadium
- Columbia, SC
| SECN | W 44–31 | 76,650 |
| November 26 | 7:30 p.m. | at No. 4 Clemson* | | ESPN | L 7–56 | 81,542 |
| December 29 | 2:00 p.m. | vs. No. 25 South Florida* | | ESPN | L 39–46 OT | 31,229 |
- *Non-conference game
Homecoming- Rankings from AP Poll released prior to game
- All times are in Eastern time
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- ^[a]The game between South Carolina and Georgia on October 8, 2016, was postponed due to Hurricane Matthew, and was rescheduled the following day on October 9, 2016.
- Schedule source:[9]