2017 Knoxville Challenger

Country	Player	Rank1	Seed
USA	Tennys Sandgren	96	1
SUI	Henri Laaksonen	97	2
USA	Taylor Fritz	105	3
GBR	Cameron Norrie	113	4
USA	Bjorn Fratangelo	118	5
USA	Stefan Kozlov	135	6
USA	Michael Mmoh	150	7
USA	Tommy Paul	159	8

• ¹ Rankings are as of October 30, 2017.^[1]

The following players received wildcards into the singles main draw:

• Jared Hiltzik
• Ronnie Schneider
• Timo Stodder
• Luis Valero

The following player received entry into the singles main draw using a protected ranking:

• Bradley Klahn

The following player received entry into the singles main draw as an alternate:

• Dennis Novikov

The following players received entry from the qualifying draw:

• Mats Moraing
• Frederik Nielsen
• Filip Peliwo
• Alexander Ward

The following player received entry as a lucky loser:

• Edward Corrie

• Filip Peliwo def. Denis Kudla 6–4, 6–2.

Leander Paes / Purav Raja def. James Cerretani / John-Patrick Smith 7–6^(7–4), 7–6^(7–4).