2C-G-5
Pharmaceutical compound
From Wikipedia, the free encyclopedia
2C-G-5, also known as 3,4-norbornyl-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families.[3][1][4][5][6][2] It is one of several homologues of 2C-G (3,4-dimethyl-2,5-dimethoxyphenethylamine).[1][4][5][6] The drug is taken orally.[1][4][5] 2C-G-5 was encountered online as a novel designer drug in 2025.[2]
- None
 | |
 | |
| Clinical data | |
|---|---|
| Other names | 3,4-Norbornyl-2,5-DMPEA; 3,4-Norbornyl-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-3,4-norbornylphenethylamine; 3,6-Dimethoxy-4-(2-aminoethyl)benzonorbornane |
| Routes of administration | Oral[1] |
| Drug class | Serotonergic psychedelic; Hallucinogen |
| ATC code |
|
| Pharmacokinetic data | |
| Onset of action | 1–2 hours[1][2] |
| Duration of action | 32–48 hours[1][2] |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| Formula | C15H21NO2 |
| Molar mass | 247.338 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
Use and effects
In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists 2C-G-5's dose as 10 to 16 mg orally and its duration as 32 to 48 hours.[3][1][4][5][2] The drug's onset is 1 to 2 hours and its time to peak is 2.5 to 3 hours.[1][2] 2C-G-5 is reported to produce psychedelic effects including visuals, clear and cosmic thinking, and 2C-B-like enhanced eroticism, among others.[1][2] It is among the most potent of the 2C psychedelics.[1][4][5] However, its duration is described as too long, interfering with sleep and resulting in subsequent-day consequences like tiredness and sleepiness.[1][2] 2C-G-5 was also the longest-lasting drug included in PiHKAL based on its specified duration.[3][1]
Interactions
Pharmacology
Data on the pharmacology and toxicology of 2C-G-5 are unavailable.[2]
Chemistry
History
2C-G-5 was first described in the literature by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).[1][4][5][6][2] It was encountered online as a novel designer drug in 2025.[2]
Society and culture
Legal status
Canada
2C-G-5 is a controlled substance in Canada under phenethylamine blanket-ban language.[7]
United States
2C-G-5 is not an explicitly controlled substance in the United States.[8] However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.