2C-T-9
Pharmaceutical compound
From Wikipedia, the free encyclopedia
2C-T-9, also known as 4-tert-butylthio-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families.[1][2][3] It is taken orally.[1][2]
- None
 | |
| Clinical data | |
|---|---|
| Other names | 4-tert-Butylthio-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-tert-butylthiophenethylamine |
| Routes of administration | Oral[1][2] |
| Drug class | Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen |
| ATC code |
|
| Pharmacokinetic data | |
| Duration of action | 12–18 hours[1][2] |
| Identifiers | |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| Formula | C14H23NO2S |
| Molar mass | 269.40 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
Use and effects
According to Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved), the dose range of 2C-T-9 is 60 to 100 mg orally and its duration is 12 to 18 hours.[1][2][4] Its effects included impairment such that one would not feel comfortable to drive, more effects "to the body than to the head", "body energy", sleeping difficulties, and hangover.[1] The drug did not produce psychedelic visuals.[1] One of the reports of 2C-T-9 was rated as a "plus-three" on the Shulgin Rating Scale.[1]
Interactions
Pharmacology
Pharmacodynamics
2C-T-9 has been found to act as a serotonin 5-HT2A receptor agonist with modest potency (EC50 = 150 nM).[5] The drug failed to produce the head-twitch response, a behavioral proxy of psychedelic effects, in rodents at the assessed dose of 3 mg/kg, which was said to parallel its known low potency in humans.[5]
Chemistry
Synthesis
The chemical synthesis of 2C-T-9 has been described.[1]
History
2C-T-9 was first described in the scientific literature by Alexander Shulgin and colleagues in 1991.[3][1] This included in a journal article[3] and in his book PiHKAL (Phenethylamines I Have Known and Loved).[1]
Society and culture
Legal status
Canada
2C-T-9 is a controlled substance in Canada under phenethylamine blanket-ban language.[6]