2CT4-2-EtO
Pharmaceutical compound
From Wikipedia, the free encyclopedia
2CT4-2-EtO, also known as 2-ethoxy-5-methoxy-4-isopropylthiophenethylamine or as Tenderness, is a psychoactive drug of the phenethylamine, 2C, and TWEETIO families related to the psychedelic drug 2C-T-4.[1][2][3] It is the derivative of 2C-T-4 in which the methoxy group at the 2 position has been replaced with an ethoxy group.[1][2][3]
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| Clinical data | |
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| Other names | 2CT4-2EtO; 2CT4-2-ETO; 2CT-4-2-ETO; 2C-T-4-2-EtO; 2-Ethoxy-5-methoxy-4-isopropylthiophenethylamine; 2-Ethoxy-4-isopropylthio-5-methoxyphenethylamine; Tenderness |
| Routes of administration | Oral[1][2][3] |
| Drug class | Psychoactive drug |
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| Pharmacokinetic data | |
| Duration of action | ~10 hours[1][2][3] |
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| Chemical and physical data | |
| Formula | C14H23NO2S |
| Molar mass | 269.40 g·mol−1 |
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According to Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, 2CT4-2-EtO's dose is 10 to 25 mg orally and its duration is approximately 10 hours.[1][2][3] Doses between 10 and 25 mg with 5-mg increments resulted in virtually no differences in effects or duration, with a gentle "plus-two" on the Shulgin Rating Scale being reached independently of dose.[1] However, in another publication, Shulgin stated that the dose affected the duration only.[2] The effects of 2CT4-2-EtO have been reported to include "a peaceful meditative inner receptiveness and clarity" and "an honest connection felt with those who were present during the experience".[1][2][3] This resulted in the drug being given the nickname "Tenderness".[1] 2CT4-2-EtO also caused uncomfortable sleep.[1]
The chemical synthesis of 2CT4-2-EtO has been described.[1]
2CT4-2-EtO was first described in the literature by Shulgin in PiHKAL in 1991.[1] It was developed and tested by Darrell Lemaire, with publication via personal communication with Shulgin.[2][4][5][6][7] The drug is a controlled substance in Canada under phenethylamine blanket-ban language.[8]