3-Methyl-PCPy

3-Me-PCPy
Clinical data
ATC code	None;
Legal status
Legal status	CA: Schedule I; DE: NpSG (Industrial and scientific use only); UK: Class B;
Identifiers
	IUPAC name 1-[1-(3-methylphenyl)cyclohexyl]pyrrolidine;
CAS Number	1622348-63-3 ;
PubChem CID	137332188;
ChemSpider	129433265;
UNII	FS9Z5C7CQ5;
CompTox Dashboard (EPA)	DTXSID201337066 ;
Chemical and physical data
Formula	C17H25N
Molar mass	243.394 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC(=CC=C1)C2(CCCCC2)N3CCCC3;
	InChI InChI=1S/C17H25N/c1-15-8-7-9-16(14-15)17(10-3-2-4-11-17)18-12-5-6-13-18/h7-9,14H,2-6,10-13H2,1H3; Key:JZVMREFYFTZXGN-UHFFFAOYSA-N;

3-Methyl-PCPy (3-Me-PCPy) is an arylcyclohexylamine derivative with an unusual spectrum of pharmacological effects, acting as both a potent NMDA antagonist and also a triple reuptake inhibitor which inhibits reuptake of all three monoamine neurotransmitters serotonin, dopamine and noradrenaline. It also acts as a high affinity sigma receptor ligand, selective for the σ₂ subtype. It produces both stimulant and dissociative effects in animal behavioural studies.^[1]^[2]^[3]