3-Thioisomescaline
Pharmaceutical compound
From Wikipedia, the free encyclopedia
3-Thioisomescaline (3-TIM), also known as 2,4-dimethoxy-3-methylthiophenethylamine, is a chemical compound of the phenethylamine and scaline families related to mescaline.[1][2][3][4] It is the analogue of isomescaline in which the methoxy group at the 3 position has been replaced with a methylthio group.[1][2][3] The compound is one of two possible thioisomescaline (TIM) positional isomers, the others being 3-thioisomescaline (3-TIM) and 4-thioisomescaline (4-TIM).[1][2][3][4]
- None
 | |
| Clinical data | |
|---|---|
| Other names | 3-TIM; 2,4-Dimethoxy-3-methylthiophenethylamine; 3-Methylthio-2,4-dimethoxyphenethylamine |
| Routes of administration | Oral[1] |
| ATC code |
|
| Pharmacokinetic data | |
| Duration of action | Unknown[1] |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| ChEMBL | |
| Chemical and physical data | |
| Formula | C11H17NO2S |
| Molar mass | 227.32 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists 3-TIM's dose as greater than 240 mg orally and its duration as unknown.[1][2][3] The effects of 3-TIM have been reported to include possible brief alert and mild stomach upset, with no other effects observed.[1] However, it is unclear that the preceding effects were actually caused by 3-TIM.[1] Shulgin concluded that 3-TIM is inactive.[2]
The chemical synthesis of 3-TIM has been described.[1][4]
3-TIM was first described in the scientific literature by Shulgin and Peyton Jacob III in 1981.[4] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.[1]