3-dehydroquinate synthase II
Class of enzymes
From Wikipedia, the free encyclopedia
3-dehydroquinate synthase II (EC 1.4.1.24, DHQ synthase II, MJ1249 (gene), aroB' (gene)) is an enzyme with systematic name 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate:NAD+ oxidoreductase (deaminating).[1] This enzyme catalyses the following chemical reaction
The three substrates of this enzyme are 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid (1), water, and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 3-dehydroquinic acid, ammonia, reduced NADH, and a proton.[2] It was isolated from the archaeon Methanocaldococcus jannaschii.[1]
