4,5-DHP-DMT

4,5-DHP-DMT
Clinical data
Other names	4,5-Dihydropyrano-N,N-dimethyltryptamine
Identifiers
	IUPAC name 1-(2-Dimethylaminoethyl)-8,9-dihydropyrano[3,2-e]indole;
CAS Number	135360-97-3 ;
PubChem CID	15011385;
ChemSpider	19425248 ;
UNII	UW9YPK64EU;
ChEMBL	ChEMBL412876;
CompTox Dashboard (EPA)	DTXSID10566920 ;
Chemical and physical data
Formula	C15H20N2O
Molar mass	244.338 gÂ·molâ1
3D model (JSmol)	Interactive image;
	SMILES CN(C)CCc1c[nH]c3ccc2OCCCc2c13;
	InChI InChI=1S/C15H20N2O/c1-17(2)8-7-11-10-16-13-5-6-14-12(15(11)13)4-3-9-18-14/h5-6,10,16H,3-4,7-9H2,1-2H3 ; Key:RMMYVKPVLLBYDW-UHFFFAOYSA-N ;
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4,5-DHP-DMT, also known as 4,5-dihydropyrano-N,N-dimethyltryptamine, is a tricyclic tryptamine derivative which acts as a potent and reasonably selective partial agonist for the serotonin receptor 5-HT_2A, with a K_i of 17.0 nM, and moderate selectivity over related serotonin receptors. It has lower 5-HT₂ affinity and efficacy than the related compound AL-37350A, but higher lipophilicity.^[1]^[2]