4-Fluorodeprenyl
Pharmaceutical compound
From Wikipedia, the free encyclopedia
4-Fluorodeprenyl, or p-F-deprenyl, also known as fludeprenyl or as N-methyl-N-propargyl-4-fluoroamphetamine, is a stimulant and monoamine oxidase inhibitor (MAOI) of the amphetamine family.[1][2][3][4] It is the 4-fluoro derivative of deprenyl and the racemic form of 4-fluoroselegiline.[3][4][2] The drug is metabolized into the stimulants 4-fluoroamphetamine (4-FA) and 4-fluoromethamphetamine (4-FMA) and hence acts in part as a prodrug of these metabolites.[3][4][1][2] Accordingly, it produces methamphetamine-like effects in drug discrimination tests in squirrel monkeys.[1][2] Like deprenyl and selegiline (L-deprenyl), 4-fluorodeprenyl is additionally a selective and irreversible inhibitor of monoamine oxidase B (MAO-B).[4] The drug was encountered as a novel designer drug in Germany in 2019.[4]
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| Other names | p-F-Depreny; Fludeprenyl; N-Methyl-N-propargyl-4-fluoroamphetamine; N-Propargyl-4-fluoromethamphetamine; N-Propargyl-4-FMA |
| Drug class | Stimulant; Monoamine oxidase inhibitor; MAO-B inhibitor |
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| Formula | C13H16FN |
| Molar mass | 205.276 g·mol−1 |
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