5-Chlorouracil

From Wikipedia, the free encyclopedia

5-Chlorouracil
Names
Preferred IUPAC name
5-Chloropyrimidine-2,4(1H,3H)-dione
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.015.763 Edit this at Wikidata
EC Number
  • 217-339-7
UNII
  • InChI=1S/C4H3ClN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
    Key: ZFTBZKVVGZNMJR-UHFFFAOYSA-N
  • C1=C(C(=O)NC(=O)N1)Cl
Properties
C4H3ClN2O2
Molar mass 146.53 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

5-Chlorouracil is an organochlorine compound that is a chlorinated version of the nucleobase uracil.[1] It is a marker for DNA damage caused by hypochlorous acid.[2] In vivo, it is converted into mutagenic chlorodeoxyuridine.[3]

References

Related Articles

Wikiwand AI