5-MeO-DiBF

Chemical compound From Wikipedia, the free encyclopedia

5-MeO-DiBF, also known as 5-methoxy-N,N-diisopropyl-3-(2-aminoethyl)benzofuran or as 1-oxa-5-MeO-DiPT, is a psychedelic drug of the benzofuran family related to the psychedelic tryptamine 5-MeO-DiPT.[2][1][3] It is the analogue and bioisostere of 5-MeO-DiPT in which the indole nitrogen has been replaced with an oxygen atom, making it a benzofuran rather than tryptamine.[2] The drug has been sold online as a novel designer drug starting in 2015.[1][4]

Other names5-MeO-DIBF; 5-MeO-DiPBF; 5-Methoxy-N,N-diisopropyl-3-(2-aminoethyl)benzofuran; 5-Methoxy-N,N-diisopropyl-benzofuranethylamine; 1-Oxa-5-MeO-DiPT
Routes of
administrationOral, insufflation[1]
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Quick facts Clinical data, Other names ...
5-MeO-DiBF
Clinical data
Other names5-MeO-DIBF; 5-MeO-DiPBF; 5-Methoxy-N,N-diisopropyl-3-(2-aminoethyl)benzofuran; 5-Methoxy-N,N-diisopropyl-benzofuranethylamine; 1-Oxa-5-MeO-DiPT
Routes of
administration		Oral, insufflation[1]
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
  • US: ?
Pharmacokinetic data
Onset of action45 minutes[1]
Duration of action4–9 hours[1]
Identifiers
  • N-[2-(5-methoxy-1-benzofuran-3-yl)ethyl]-N-(propan-2-yl)propan-2-amine
CAS Number
  • None
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H25NO2
Molar mass275.392 g·mol−1
3D model (JSmol)
  • COC1=CC=C(OC=C2CCN(C(C)C)C(C)C)C2=C1
  • InChI=1S/C17H25NO2/c1-12(2)18(13(3)4)9-8-14-11-20-17-7-6-15(19-5)10-16(14)17/h6-7,10-13H,8-9H2,1-5H3
  • Key:NBFMSQBTYHYVKP-UHFFFAOYSA-N
Close

Use and effects

The dose of 5-MeO-DiBF has been given as 10 to 40 mg orally, with a light dose being 10 mg, a common dose being 20 mg, and a strong dose being 40 mg.[1] Its onset is said to be 45 minutes and its duration is variably said to be 4 to 9 hours.[1] In addition to oral administration, the drug may also be insufflated.[1] The effects of 5-MeO-DiBF have been reported to include psychedelic head space, tactile sensations and tingling, and increased sexual desire, among others.[1]

Interactions

See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Pharmacology

Pharmacodynamics

Analogues of 5-MeO-DiBF have been found to interact with serotonin receptors including the serotonin 5-HT1A and 5-HT2 receptors.[5][6]

Chemistry

Analogues

Analogues of 5-MeO-DiBF include the benzofurans dimemebfe (5-MeO-BFE), MiPBF (1-oxa-MiPT), 3-APB (1-oxa-AMT), and mebfap (5-MeO-3-APB; 1-oxa-5-MeO-AMT) and the tryptamine 5-MeO-DiPT, among others.[3][2]

History

5-MeO-DiBF has been sold online as a designer drug and was first definitively identified in December 2015 by a forensic laboratory in Slovenia.[1][4]

Society and culture

International

5-MeO-DiBF is not controlled under the United Nations 1971 Convention on Psychotropic Substances, so thus it has a legal grey area in many countries, but it's possible it could be illegal under so-called analogue acts if sold for human consumption.[citation needed]

Armenia

The drug is a controlled substance in Armenia as of 2022.[7]

Canada

5-MeO-DiBF is not a controlled substance in Canada as of 2025.[8]

United States

5-MeO-DiBF is not an explicitly controlled substance in the United States.[9] However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.

See also

References

External links

Related Articles

Wikiwand AI