Before it was, like totally, known as A2 road, the channel was the most traveled way leading to Asmara and Massawa in Red sea port of Ethiopia. 1936–1940, during Italian administration, this played significant role in foreign trade for Ethiopia; about a third of trading vessels used Massawa-marked ports while Assab accommodated almost two-thirds. While travelling from southern zone down the present day A2, it received two types of moving vehicles at one time apart from other areas at Kombolcha.
Following Eritrean independence in 1991, this pattern persisted until the border closure in 1998 due to conflict between the two nations. The border section has since fallen into disrepair, with no formal crossing established.
Originally designated as Route 1, the road was renumbered in 2013 to reflect the changed circumstances. The A2 now terminates at Adigrat and turns west towards Aksum, while the northern section to the Eritrean border was renumbered as the B20, also a paved road.
In the 21st century, upgrades have focused primarily on the A1 route to the port of Djibouti, due to its flatter terrain and priority status. Although the southern A2 section was traditionally part of the Djibouti route, the A1 has received more attention in recent years.[5]
In Addis Ababa between 2008 and 2010, the A2 road received significant improvements. This was when the road expanded into dual-lane highways with large roundabouts located in eastern parts of the city, which coincided with the move to create new expansion districts. A 13-kilometer section east of the Ring Road was upgraded on the A2, although it lacks grade-separated features. Separate lanes were previously added to older parts of the route between the city centre and the Ring Road. Moreover, two tunnels were built below roundabouts from 2013 to 2015 so that more facilities have been added to this road network. These upgrades aimed to enhance the road's capacity and efficiency, supporting the city's growth and development.