AC-263093

AC-263093 is a drug used in scientific research which acts as an agonist at the neuropeptide FF receptor NPFF2 and an antagonist for the closely related NPFF1 receptor. In animal studies it reduced tolerance to morphine but also produced hyperalgesia and anxiety.^[1][2][3][4] Related compounds such as AC-099 with Cl or CF3 replacing the bromine substituents have similar activity as NPFF2 agonists or partial agonists but with relatively lower potency.^[5]

CAS Number

• 849459-86-5

PubChem CID

• 44542176

ChemSpider

• 24636697

ChEMBL

• ChEMBL573297

Quick facts Identifiers, CAS Number ...

AC-263093

Identifiers
IUPAC name 2-[(E)-(3,4-dibromophenyl)methylideneamino]guanidine
CAS Number	849459-86-5
PubChem CID	44542176
ChemSpider	24636697
ChEMBL	ChEMBL573297
Chemical and physical data
Formula	C8H8Br2N4
Molar mass	319.988 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=CC(=C(C=C1/C=N/N=C(N)N)Br)Br
InChI InChI=1S/C8H8Br2N4/c9-6-2-1-5(3-7(6)10)4-13-14-8(11)12/h1-4H,(H4,11,12,14)/b13-4+ Key:VMYFCUKMGMFQNH-YIXHJXPBSA-N

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