AC927
Chemical compound
From Wikipedia, the free encyclopedia
AC927 or 1-(2-phenylethyl)piperidine is a selective sigma receptor antagonist, with reported binding affinity of Ki = 30 ± 2 nM for the sigma-1 receptor and Ki = 138 ± 18 nM for the sigma-2 receptor, and negligible binding affinity for other major central nervous system receptors, transporters, and ion channels.[1]
Other names1-Phenethylpiperidine; pip-PEA; Phenylethylpiperidine
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| Other names | 1-Phenethylpiperidine; pip-PEA; Phenylethylpiperidine |
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| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.005.785 |
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| Formula | C13H19N |
| Molar mass | 189.302 g·mol−1 |
AC927 is reported to attenuate the locomotor stimulation induced by methamphetamine in mice.[1]