ACAA1

ACAA1
Identifiers
Aliases	ACAA1, ACAA, PTHIO, THIO, acetyl-CoA acyltransferase 1, Lnc-Myd88
External IDs	OMIM: 604054; MGI: 2148491; GeneCards: ACAA1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2IIK
Enzyme activity
Gene location (Human)
Chr.	Chromosome 3 (human)
End	38,137,242 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	119,179,365 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; right lobe of liver; ; mucosa of transverse colon; ; duodenum; ; kidney tubule; ; human kidney; ; renal medulla; ; apex of heart; ; granulocyte; ; body of pancreas;
	Top expressed in
	Ileal epithelium; ; lip; ; right kidney; ; choroid plexus of fourth ventricle; ; motor neuron; ; aortic valve; ; interventricular septum; ; corneal stroma; ; ascending aorta; ; fossa;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; acyltransferase activity, transferring groups other than amino-acyl groups; protein binding; catalytic activity; palmitoyl-CoA oxidase activity; acyltransferase activity; acetate CoA-transferase activity; acetyl-CoA C-acyltransferase activity;
Cellular component	membrane; intracellular membrane-bounded organelle; peroxisome; peroxisomal matrix; extracellular region; specific granule lumen; cytosol;
Biological process	lipid metabolism; bile acid metabolic process; alpha-linolenic acid metabolic process; very long-chain fatty acid metabolic process; fatty acid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid beta-oxidation; metabolism; neutrophil degranulation; protein targeting to peroxisome; phenylacetate catabolic process;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	30
	113868
	ENSG00000060971
	ENSMUSG00000036138
	P09110
	Q921H8
	NM_001130410; NM_001607
	NM_130864; NM_001357516
	NP_001123882; NP_001598; NP_001598.1
	NP_570934; NP_001344445
	Wikidata
View/Edit Human	View/Edit Mouse

3-Ketoacyl-CoA thiolase, peroxisomal also known as acetyl-Coenzyme A acyltransferase 1 is an enzyme that in humans is encoded by the ACAA1 gene.^[5]^[6]^[7]