ACBD3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Golgi resident protein GCP60 is a protein that in humans is encoded by the ACBD3 gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesACBD3, GCP60, GOCAP1, GOLPH1, PAP7, acyl-CoA binding domain containing 3
Quick facts Available structures, PDB ...
ACBD3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesACBD3, GCP60, GOCAP1, GOLPH1, PAP7, acyl-CoA binding domain containing 3
External IDsOMIM: 606809; MGI: 2181074; HomoloGene: 11227; GeneCards: ACBD3; OMA:ACBD3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_022735

NM_133225

RefSeq (protein)

NP_073572
NP_073572.2

NP_573488

Location (UCSC)Chr 1: 226.14 – 226.19 MbChr 1: 180.55 – 180.58 Mb
PubMed search[3][4]
Wikidata
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Function

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. ACBD3 is involved in maintaining the Golgi structure by interacting with giantin, which affects the transport of protein.[6] The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation.[5]

Interactions

ACBD3 has been shown to interact with GOLGB1.[7]

References

Further reading

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