ACSL6

ACSL6
Identifiers
Aliases	ACSL6, ACS2, FACL6, LACS 6, LACS2, LACS5, acyl-CoA synthetase long-chain family member 6, acyl-CoA synthetase long chain family member 6
External IDs	OMIM: 604443; MGI: 894291; HomoloGene: 100939; GeneCards: ACSL6; OMA:ACSL6 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	132,012,243 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	54,364,756 bp
RNA expression pattern
	Top expressed in
	lateral nuclear group of thalamus; ; Brodmann area 23; ; primary visual cortex; ; right hemisphere of cerebellum; ; pons; ; seminal vesicula; ; Brodmann area 9; ; endothelial cell; ; right frontal lobe; ; left testis;
	Top expressed in
	olfactory epithelium; ; retinal pigment epithelium; ; deep cerebellar nuclei; ; central gray substance of midbrain; ; medial vestibular nucleus; ; dorsal tegmental nucleus; ; anterior horn of spinal cord; ; inferior colliculi; ; pontine nuclei; ; neural layer of retina;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; protein homodimerization activity; ligase activity; catalytic activity; enzyme binding; ATP binding; decanoate-CoA ligase activity; long-chain fatty acid-CoA ligase activity;
Cellular component	organelle membrane; integral component of membrane; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; plasma membrane; peroxisomal membrane; peroxisome; mitochondrial outer membrane; endoplasmic reticulum; mitochondrion;
Biological process	acyl-CoA metabolic process; lipid metabolism; fatty acid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; metabolism; long-chain fatty acid metabolic process; neuroblast proliferation;
	Sources:Amigo / QuickGO
Orthologs
	23305
	216739
	ENSG00000164398
	ENSMUSG00000020333
	Q9UKU0
	Q91WC3
NM_015256; NM_001009185; NM_001205247; NM_001205248; NM_001205250;
	NM_001205251
	NM_001033597; NM_001033598; NM_001033599; NM_144823
NP_001009185; NP_001192176; NP_001192177; NP_001192179; NP_001192180;
	NP_056071
	NP_001028769; NP_001028770; NP_001028771; NP_659072
	Wikidata
View/Edit Human	View/Edit Mouse

Acyl-CoA synthetase long-chain family member 6 is an enzyme that in humans is encoded by the ACSL6 gene.^[5]^[6]^[7] Long-chain acyl-CoA synthetases such as ACSL6, catalyze the formation of acyl-CoA from fatty acids, ATP, and CoA.^[6]