ACSS3

ACSS3
Identifiers
Aliases	ACSS3, acyl-CoA synthetase short-chain family member 3, acyl-CoA synthetase short chain family member 3
External IDs	OMIM: 614356; MGI: 2685720; HomoloGene: 11587; GeneCards: ACSS3; OMA:ACSS3 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	81,261,210 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	106,959,529 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; parotid gland; ; liver; ; Achilles tendon; ; corpus epididymis; ; left adrenal gland; ; right lobe of liver; ; caput epididymis; ; right adrenal cortex; ; left adrenal cortex;
	Top expressed in
	white adipose tissue; ; otolith organ; ; utricle; ; brown adipose tissue; ; intercostal muscle; ; gastrula; ; mammary gland; ; subcutaneous adipose tissue; ; Epithelium of choroid plexus; ; olfactory epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; ligase activity; catalytic activity; ATP binding; acetate-CoA ligase activity;
Cellular component	mitochondrion; mitochondrial matrix;
Biological process	metabolism; ketone body biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	79611
	380660
	ENSG00000111058
	ENSMUSG00000035948
	Q9H6R3
	Q14DH7
	NM_024560; NM_001330242; NM_001330243
	NM_001142804; NM_198636
	NP_001317171; NP_001317172; NP_078836
	NP_001136276; NP_941038
	Wikidata
View/Edit Human	View/Edit Mouse

AliasesACSS3, acyl-CoA synthetase short-chain family member 3, acyl-CoA synthetase short chain family member 3

External IDsOMIM: 614356; MGI: 2685720; HomoloGene: 11587; GeneCards: ACSS3; OMA:ACSS3 - orthologs

Chr.Chromosome 12 (human)^[1]

End81,261,210 bp^[1]

Acyl-CoA synthetase short-chain family member 3 is a protein that in humans is encoded by the ACSS3 gene.^[5]

[1]

[2]

[3]

[4]

[5]

v t e Enzymes: CO CS and CN ligases (EC 6.1-6.3)
6.1: Carbon-Oxygen	Aminoacyl tRNA synthetase Alanine Arginine Asparagine Aspartate Cysteine D-alanine—poly(phosphoribitol) ligase Glutamate Glutamine Glycine Histidine Isoleucine Leucine Lysine Methionine Phenylalanine Proline Serine Threonine Tryptophan Tyrosine Valine
6.2: Carbon-Sulfur	(2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase 2-furoate—CoA ligase 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate—CoA ligase 3-hydroxybenzoate—CoA ligase 3-hydroxypropionyl-CoA synthase 4-chlorobenzoate—CoA ligase 4-Coumarate-CoA ligase 4-hydroxybenzoate—CoA ligase 6-carboxyhexanoate—CoA ligase Acetate—ACP ligase Acetate—CoA ligase (ADP-forming) Acetoacetate—CoA ligase Acetyl—CoA synthetase Acid—CoA ligase (GDP-forming) Anthranilate—CoA ligase Arachidonate—CoA ligase Benzoate—CoA ligase Biotin—CoA ligase (butirosin acyl-carrier protein)—L-glutamate ligase Butyrate—CoA ligase Cholate—CoA ligase Citrate—CoA ligase (citrate (pro-3S)-lyase) ligase Dicarboxylate—CoA ligase Glutarate—CoA ligase Long-chain-fatty-acid—ACP ligase Long-chain-fatty-acid—CoA ligase Malate—CoA ligase Malonate—CoA ligase O-succinylbenzoate—CoA ligase Oxalate—CoA ligase Phenylacetate—CoA ligase Phytanate—CoA ligase Propionate—CoA ligase Succinate—CoA ligase (ADP-forming) Succinate—CoA ligase (GDP-forming) Succinyl—CoA synthetase Trans-feruloyl-CoA synthase
6.3: Carbon-Nitrogen	Glutamine synthetase Ubiquitin ligase Cullin Von Hippel–Lindau tumor suppressor UBE3A Mdm2 Anaphase-promoting complex UBR1 Glutathione synthetase CTP synthetase Adenylosuccinate synthase Argininosuccinate synthase Holocarboxylase synthetase GMP synthase Asparagine synthetase Carbamoyl phosphate synthetase I II Glutamate–cysteine ligase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

ACSS3

References

Further reading

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