ACTR3

Mammalian protein found in Homo sapiens From Wikipedia, the free encyclopedia

Actin-related protein 3 is a protein that in humans is encoded by the ACTR3 gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesACTR3, ARP3, ARP3 actin-related protein 3 homolog (yeast), ARP3 actin related protein 3 homolog, actin related protein 3
Quick facts Available structures, PDB ...
ACTR3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesACTR3, ARP3, ARP3 actin-related protein 3 homolog (yeast), ARP3 actin related protein 3 homolog, actin related protein 3
External IDsOMIM: 604222; MGI: 1921367; HomoloGene: 68483; GeneCards: ACTR3; OMA:ACTR3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001277140
NM_005721

NM_001205385
NM_001205386
NM_023735

RefSeq (protein)

NP_001264069
NP_005712

NP_001192314
NP_001192315
NP_076224

Location (UCSC)Chr 2: 113.89 – 113.96 MbChr 1: 125.32 – 125.36 Mb
PubMed search[3][4]
Wikidata
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Function

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.[6]

Interactions

ACTR3 has been shown to interact with Cortactin.[7][8]

References

Further reading

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