AH-7614

Pharmaceutical compound From Wikipedia, the free encyclopedia

AH-7614 is an experimental drug which acts as a potent and selective antagonist for the free fatty acid receptor FFAR4 (GPR120), though it has also been described as an inverse agonist or negative allosteric modulator.[1][2] Agonists of FFAR4 have antiinflammatory effects and are of interest in the treatment of various conditions including diabetes and obesity, and as a selective FFAR4 antagonist AH-7614 is important for research into the function of this receptor.[3][4][5][6]

CAS Number
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AH-7614
Identifiers
  • 4-methyl-N-(9H-xanthen-9-yl)benzenesulfonamide
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC20H17NO3S
Molar mass351.42 g·mol−1
3D model (JSmol)
  • CC1=CC=C(C=C1)S(=O)(=O)NC2C3=CC=CC=C3OC4=CC=CC=C24
  • InChI=1S/C20H17NO3S/c1-14-10-12-15(13-11-14)25(22,23)21-20-16-6-2-4-8-18(16)24-19-9-5-3-7-17(19)20/h2-13,20-21H,1H3
  • Key:OZCQEUZTOAAWDK-UHFFFAOYSA-N
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