AKAP1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

A kinase anchor protein 1, mitochondrial is an enzyme that in humans is encoded by the AKAP1 gene.[5][6][7]

AliasesAKAP1, AKAP, AKAP121, AKAP149, AKAP84, D-PPP1R43, PRKA1, SAKAP84, TDRD17, A-kinase anchoring protein 1
End57,121,346 bp[1]
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AKAP1
Identifiers
AliasesAKAP1, AKAP, AKAP121, AKAP149, AKAP84, D-PPP1R43, PRKA1, SAKAP84, TDRD17, A-kinase anchoring protein 1
External IDsOMIM: 602449; MGI: 104729; HomoloGene: 31165; GeneCards: AKAP1; OMA:AKAP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001042541
NM_009648

RefSeq (protein)

NP_001036006
NP_033778

Location (UCSC)Chr 17: 57.09 – 57.12 MbChr 11: 88.72 – 88.76 Mb
PubMed search[3][4]
Wikidata
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Function

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins that have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.[7]

Interactions

AKAP1 has been shown to interact with:

References

Further reading

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