AKAP7

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

A-kinase anchor protein 7 isoform gamma is an enzyme that in humans is encoded by the AKAP7 gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesAKAP7, AKAP15, AKAP18, A-kinase anchoring protein 7
Quick facts Available structures, PDB ...
AKAP7
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAKAP7, AKAP15, AKAP18, A-kinase anchoring protein 7
External IDsOMIM: 604693; MGI: 1859150; HomoloGene: 49463; GeneCards: AKAP7; OMA:AKAP7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018747
NM_001347460
NM_001379238
NM_001379239
NM_001379240

RefSeq (protein)

NP_004833
NP_057461
NP_619539
NP_001363499
NP_057461.2

Location (UCSC)Chr 6: 131.14 – 131.28 MbChr 10: 25.04 – 25.18 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations.[6]

References

Further reading

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